What is an ethical problem with placebo-controlled studies?
(A) Patients who could benefit from the experimental treatment may be selected for the placebo treatment.
(B) Placebo treatments do not effectively control for the "placebo effect" when the subject does not know which treatment he is receiving.
(C) With a placebo-controlled study, a randomized comparative experiment is impossible.
(D) It is logistically impossible to give some patients a placebo.
Answer: (A) Patients who could benefit from the experimental treatment may be selected for the placebo treatment.
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